one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity related to bortezomib, a proteasome inhibitor Employed in the procedure of multiple myeloma. Its synthesis or analyze is crucial for making sure the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A important compound during the synthesis of imatinib, a drug that targets distinct forms of most cancers, which includes Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their study is important for optimizing the generation process and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is employed to take care of breast most (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4 cancers, and these intermediates are involved with its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the cure of breast most cancers. Several intermediates assist in the synthesis of CAS NO. 314771-76-1 this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the procedure of colorectal most cancers and compact cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, which have several applications, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for variety 2 diabetic issues that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication applied to control variety two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).